TRT Authority
Glossary Term

Selective Estrogen Receptor Modulator

MD

Reviewed By

TRT Authority Medical Team

Selective Estrogen Receptor Modulator (SERM) is a class of drugs that blocks or activates estrogen receptors in specific tissues. Clomiphene citrate, used in TRT, acts as a SERM to stimulate the pituitary gland and boost natural testosterone production without external hormone replacement.

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