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💉 Erectile Dysfunction

Injectable ED Treatments

Comprehensive guide to injectable ed treatments options for TRT patients.

2 medications

Medications

$100

PT-141 (Bremelanotide)

Vyleesi (FDA-approved for women), compounded for men

A melanocortin receptor agonist that works on the central nervous system rather than the vascular system to improve sexual desire and arousal. Unlike PDE5 inhibitors which address the mechanical aspect of erections, PT-141 targets the brain's sexual response pathways. Administered via subcutaneous injection approximately 45 minutes before anticipated sexual activity. Particularly useful for men who don't respond to PDE5 inhibitors or who have low desire alongside ED.

2.7 hours As Needed
$100

Trimix

Compounded only (various pharmacies)

A compounded injectable medication containing three vasodilators - alprostadil (prostaglandin E1), papaverine, and phentolamine - injected directly into the corpus cavernosum of the penis. Considered the most effective pharmaceutical ED treatment available, with success rates exceeding 90%. Typically reserved for men who fail PDE5 inhibitors. Requires careful dose titration to avoid priapism.

1-3 hours (effect duration) As Needed

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Disclaimer: This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.