Injectable Testosterone
Comprehensive guide to injectable testosterone options for TRT patients.
Medications
Testosterone Cypionate
Depo-Testosterone, PFIZER Cyp
The most commonly prescribed form of injectable testosterone in the United States. Testosterone cypionate is an oil-based injectable that provides steady testosterone levels when administered weekly or bi-weekly. It has a longer half-life than enanthate, making it popular for TRT protocols. Available as both brand name (Depo-Testosterone) and generic/compounded formulations.
Testosterone Enanthate
Delatestryl, Xyosted
A popular oil-based injectable testosterone with a slightly shorter half-life than cypionate. Widely used in TRT protocols, particularly outside the US where it's often more readily available. Functionally very similar to cypionate with comparable effectiveness. Often chosen based on availability and physician preference.
Testosterone Propionate
Testoviron (discontinued in US)
A fast-acting injectable testosterone ester with a very short half-life. Requires frequent injections (every other day or daily) to maintain stable levels. Rarely used for TRT due to injection frequency, but sometimes preferred by bodybuilders for precise control. May cause less water retention than longer esters.
Testosterone Undecanoate (Injectable)
Aveed (US), Nebido (international)
A long-acting injectable testosterone ester administered every 10-14 weeks by a healthcare provider. Provides very stable testosterone levels with minimal peaks and troughs due to its extended release profile. Requires an in-office injection with a mandatory 30-minute post-injection observation period due to rare but serious pulmonary oil microembolism (POME) risk. Ideal for men who want infrequent dosing but are comfortable with clinic visits.
Explore more testosterone therapy options
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